Dr. Nallasivam Palanisamy- Publications as on 10/07/2020
1-141 of 141
(Display the 141 citations in PubMed)
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Gene fusion characterisation of rare aggressive prostate cancer variants-adenosquamous carcinoma, pleomorphic giant-cell carcinoma, and sarcomatoid carcinoma: an analysis of 19 cases.Alhamar M, Tudor Vladislav I, Smith SC, Gao Y, Cheng L, Favazza LA, Alani AM, Ittmann MM, Riddle ND, Whiteley LJ, Gupta NS, Carskadon S, Gomez-Gelvez JC, Chitale DA, Palanisamy N, Hes O, Trpkov K, Williamson SR.Histopathology. 2020 Jul 8. doi: 10.1111/his.14205. Online ahead of print.PMID: 32639612. |
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The MD Anderson Prostate Cancer Patient-derived Xenograft Series (MDA PCa PDX) Captures the Molecular Landscape of Prostate Cancer and Facilitates Marker-driven Therapy Development.Palanisamy N, Yang J, Shepherd PDA, Li-Ning-Tapia EM, Labanca E, Manyam GC, Ravoori MK, Kundra V, Araujo JC, Efstathiou E, Pisters LL, Wan X, Wang X, Vazquez ES, Aparicio AM, Carskadon SL, Tomlins SA, Kunju LP, Chinnaiyan AM, Broom BM, Logothetis CJ, Troncoso P, Navone NM.Clin Cancer Res. 2020 Sep 15;26(18):4933-4946. doi: 10.1158/1078-0432.CCR-20-0479. Epub 2020 Jun 23.PMID: 32576626. |
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Molecular characterization of prostate cancer in Middle Eastern population highlights differences with Western populations with prognostic implication.Abdelsalam RA, Khalifeh I, Box A, Kalantarian M, Ghosh S, Abou-Ouf H, Lotfi T, Shahait M, Palanisamy N, Bismar TA.J Cancer Res Clin Oncol. 2020 Jul;146(7):1701-1709. doi: 10.1007/s00432-020-03221-x. Epub 2020 Apr 30.PMID: 32350606. |
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Clonal evaluation of prostate cancer molecular heterogeneity in biopsy samples by dual immunohistochemistry and dual RNA in situ hybridization.Dedigama-Arachchige P, Carskadon S, Li J, Loveless I, Alhamar M, Peabody JO, Stricker H, Chitale DA, Rogers CG, Menon M, Gupta NS, Bismar TA, Williamson SR, Palanisamy N.Mod Pathol. 2020 Sep;33(9):1791-1801. doi: 10.1038/s41379-020-0525-0. Epub 2020 Apr 1.PMID: 32238875. |
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Therapeutically actionable PAK4 is amplified, overexpressed, and involved in bladder cancer progression.Chandrashekar DS, Chakravarthi BVSK, Robinson AD, Anderson JC, Agarwal S, Balasubramanya SAH, Eich ML, Bajpai AK, Davuluri S, Guru MS, Guru AS, Naik G, Della Manna DL, Acharya KK, Carskadon S, Manne U, Crossman DK, Ferguson JE, Grizzle WE, Palanisamy N, Willey CD, Crowley MR, Netto GJ, Yang ES, Varambally S, Sonpavde G.Oncogene. 2020 May;39(20):4077-4091. doi: 10.1038/s41388-020-1275-7. Epub 2020 Mar 30.PMID: 32231273. |
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A Novel COL1A1-CAMTA1 Rearrangement in Cranial Fasciitis.Jebastin Thangaiah J, Vickery J, Selwanes W, Al-Haddad E, Perry KD, Palanisamy N, Poulik JM, Williamson SR, Chitale DA, Shehata BM.Int J Surg Pathol. 2020 Sep;28(6):678-682. doi: 10.1177/1066896920912485. Epub 2020 Mar 19.PMID: 32192385. |
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Androgen deprivation upregulates SPINK1 expression and potentiates cellular plasticity in prostate cancer.Tiwari R, Manzar N, Bhatia V, Yadav A, Nengroo MA, Datta D, Carskadon S, Gupta N, Sigouros M, Khani F, Poutanen M, Zoubeidi A, Beltran H, Palanisamy N, Ateeq B.Nat Commun. 2020 Jan 20;11(1):384. doi: 10.1038/s41467-019-14184-0.PMID: 31959826 Free PMC article. |
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High-Throughput Label-Free Isolation of Heterogeneous Circulating Tumor Cells and CTC Clusters from Non-Small-Cell Lung Cancer Patients.Zeinali M, Lee M, Nadhan A, Mathur A, Hedman C, Lin E, Harouaka R, Wicha MS, Zhao L, Palanisamy N, Hafner M, Reddy R, Kalemkerian GP, Schneider BJ, Hassan KA, Ramnath N, Nagrath S.Cancers (Basel). 2020 Jan 3;12(1):127. doi:10.3390/cancers12010127.PMID: 31947893 Free PMC article. |
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Next-generation sequencing implicates oncogenic roles for p53 and JAK/STAT signaling in microcystic adnexal carcinomas.Chan MP, Plouffe KR, Liu CJ, Palanisamy N, Carskadon S, Zhao L, Nazarian RM, Durham AB, Johnson TM, Andea AA, Patel RM, Lowe L, Fullen DR, Brown NA, Tomlins SA, Udager AM, Harms PW.Mod Pathol. 2020 Jun;33(6):1092-1103. doi: 10.1038/s41379-019-0424-4. Epub 2019 Dec 19.PMID: 31857679. |
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A Hierarchical Machine Learning Model to Discover Gleason Grade-Specific Biomarkers in Prostate Cancer.Hamzeh O, Alkhateeb A, Zheng JZ, Kandalam S, Leung C, Atikukke G, Cavallo-Medved D, Palanisamy N, Rueda L.Diagnostics (Basel). 2019 Dec 11;9(4):219. doi: 10.3390/diagnostics9040219.PMID: 31835700 Free PMC article. |
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Atypical Lipomatous Tumor/Well-Differentiated Liposarcoma With Features Mimicking Spindle Cell Lipoma.Jebastin JAS, Perry KD, Chitale DA, Mott MP, Sanchez J, Fritchie KJ, Palanisamy N, Williamson SR.Int J Surg Pathol. 2020 May;28(3):336-340. doi: 10.1177/1066896919884648. Epub 2019 Oct 31.PMID: 31672072 |
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Clonal evaluation of early onset prostate cancer by expression profiling of ERG, SPINK1, ETV1, and ETV4 on whole-mount radical prostatectomy tissue.Lu Z, Williamson SR, Carskadon S, Arachchige PD, Dhamdhere G, Schultz DS, Stricker H, Peabody JO, Jeong W, Chitale DA, Bismar TA, Rogers CG, Menon M, Gupta NS, Palanisamy N.Prostate. 2020 Jan;80(1):38-50. doi: 10.1002/pros.23914. Epub 2019 Oct 4.PMID: 31584209 |
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Eukaryotic Translation Initiation Factor 4 Gamma 1 (EIF4G1): a target for cancer therapeutic intervention?Jaiswal PK, Koul S, Palanisamy N, Koul HK.Cancer Cell Int. 2019 Aug 31;19:224. doi: 10.1186/s12935-019-0947-2. eCollection 2019.PMID: 31496918 Free PMC article. |
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CDK7 Inhibition Suppresses Castration-Resistant Prostate Cancer through MED1 Inactivation.Rasool RU, Natesan R, Deng Q, Aras S, Lal P, Sander Effron S, Mitchell-Velasquez E, Posimo JM, Carskadon S, Baca SC, Pomerantz MM, Siddiqui J, Schwartz LE, Lee DJ, Palanisamy N, Narla G, Den RB, Freedman ML, Brady DC, Asangani IA.Cancer Discov. 2019 Nov;9(11):1538-1555. doi: 10.1158/2159-8290.CD-19-0189. Epub 2019 Aug 29.PMID: 31466944 Free PMC article. |
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Pseudogene Associated Recurrent Gene Fusion in Prostate Cancer.Chakravarthi BV, Dedigama-Arachchige P, Carskadon S, Sundaram SK, Li J, Wu KH, Chandrashekar DS, Peabody JO, Stricker H, Hwang C, Chitale DA, Williamson SR, Gupta NS, Navone NM, Rogers C, Menon M, Varambally S, Palanisamy N.Neoplasia. 2019 Oct;21(10):989-1002. doi: 10.1016/j.neo.2019.07.010. Epub 2019 Aug 22.PMID: 31446281 Free PMC article. |
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A pediatric case of pigmented epithelioid melanocytoma with chromosomal copy number alterations in 15q and 17q and a novel NTRK3-SCAPER gene fusion.Friedman BJ, Hernandez S, Fidai C, Jiang A, Shwayder TA, Carskadon S, Andea AA, Harms PW, Chitale D, Palanisamy N.J Cutan Pathol. 2020 Jan;47(1):70-75. doi: 10.1111/cup.13566. Epub 2019 Sep 11.PMID: 31437301 |
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Combined loss of TFF3 and PTEN is associated with lethal outcome and overall survival in men with prostate cancer.Abou-Ouf H, Ghosh S, Box A, Palanisamy N, Bismar TA.J Cancer Res Clin Oncol. 2019 Jul;145(7):1751-1759. doi: 10.1007/s00432-019-02933-z. Epub 2019 May 25.PMID: 31129769 |
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Prostate cancer with comedonecrosis is frequently, but not exclusively, intraductal carcinoma: a need for reappraisal of grading criteria.Madan R, Deebajah M, Alanee S, Gupta NS, Carskadon S, Palanisamy N, Williamson SR.Histopathology. 2019 Jun;74(7):1081-1087. doi: 10.1111/his.13833. Epub 2019 Apr 29.PMID: 30720899 |
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Epigenetic Silencing of miRNA-338-5p and miRNA-421 Drives SPINK1-Positive Prostate Cancer.Bhatia V, Yadav A, Tiwari R, Nigam S, Goel S, Carskadon S, Gupta N, Goel A, Palanisamy N, Ateeq B.Clin Cancer Res. 2019 May 1;25(9):2755-2768. doi: 10.1158/1078-0432.CCR-18-3230. Epub 2018 Dec 26.PMID: 30587549 Free PMC article. |
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Association of ERG/PTEN status with biochemical recurrence after radical prostatectomy for clinically localized prostate cancer.Mehra R, Salami SS, Lonigro R, Bhalla R, Siddiqui J, Cao X, Spratt DE, Palapattu GS, Palanisamy N, Wei JT, Chinnaiyan AM, Tomlins SA.Med Oncol. 2018 Oct 5;35(12):152. doi: 10.1007/s12032-018-1212-6.PMID: 30291535 Free PMC article. |
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Neurofilament is superior to cytokeratin 20 in supporting cutaneous origin for neuroendocrine carcinoma.Stanoszek LM, Chan MP, Palanisamy N, Carskadon S, Siddiqui J, Patel RM, Harms KL, Lowe L, Fullen DR, Harms PW.Histopathology. 2019 Feb;74(3):504-513. doi: 10.1111/his.13758. Epub 2018 Dec 5.PMID: 30239030 |
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Clinical utility of assessing PTEN and ERG protein expression in prostate cancer patients: a proposed method for risk stratification.Bismar TA, Hegazy S, Feng Z, Yu D, Donnelly B, Palanisamy N, Trock BJ.J Cancer Res Clin Oncol. 2018 Nov;144(11):2117-2125. doi: 10.1007/s00432-018-2730-5. Epub 2018 Aug 12.PMID: 30101374 |
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Wnt receptor Frizzled 8 is a target of ERG in prostate cancer.Chakravarthi BVSK, Chandrashekar DS, Hodigere Balasubramanya SA, Robinson AD, Carskadon S, Rao U, Gordetsky J, Manne U, Netto GJ, Sudarshan S, Palanisamy N, Varambally S.Prostate. 2018 Dec;78(16):1311-1320. doi: 10.1002/pros.23704. Epub 2018 Jul 26.PMID: 30051493 |
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Expression and role of PAICS, a de novo purine biosynthetic gene in prostate cancer.Chakravarthi BVSK, Goswami MT, Pathi SS, Dodson M, Chandrashekar DS, Agarwal S, Nepal S, Hodigere Balasubramanya SA, Siddiqui J, Lonigro RJ, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S.Prostate. 2018 Jun;78(9):693-694. doi: 10.1002/pros.23533. Epub 2018 Apr 10.PMID: 29744932 No abstract available. |
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Enrichment and mutation detection of circulating tumor cells from blood samples. Kou R, Zhao J, Gogoi P, Carskadon S, Chow W, Hwang C, Palanisamy N, Leung C, Wang Y.Oncol Rep. 2018 Jun;39(6):2537-2544. doi: 10.3892/or.2018.6342. Epub 2018 Mar 30.PMID: 29620284 Free PMC article. |
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Pseudosarcomatous myofibroblastic proliferations of the genitourinary tract are genetically different from nodular fasciitis and lack USP6, ROS1 and ETV6 gene rearrangements.Jebastin JAS, Smith SC, Perry KD, Gupta NS, Alanee S, Carskadon S, Chitale DA, Palanisamy N, Williamson SR.Histopathology. 2018 Aug;73(2):321-326. doi: 10.1111/his.13526. Epub 2018 May 30.PMID: 29617048 |
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Solitary Fibrous Tumors of the Head and Neck: A Multi-Institutional Clinicopathologic Study.Smith SC, Gooding WE, Elkins M, Patel RM, Harms PW, McDaniel AS, Palanisamy N, Uram-Tuculescu C, Balzer BB, Lucas DR, Seethala RR, McHugh JB.Am J Surg Pathol. 2017 Dec;41(12):1642-1656. doi: 10.1097/PAS.0000000000000940.PMID: 28877055 Free PMC article. |
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Increased expression of EZH2 in Merkel cell carcinoma is associated with disease progression and poorer prognosis.Harms KL, Chubb H, Zhao L, Fullen DR, Bichakjian CK, Johnson TM, Carskadon S, Palanisamy N, Harms PW.Hum Pathol. 2017 Sep;67:78-84. doi: 10.1016/j.humpath.2017.07.009. Epub 2017 Jul 21.PMID: 28739498 |
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Renal cell tumors with clear cell histology and intact VHL and chromosome 3p: a histological review of tumors from the Cancer Genome Atlas database.Favazza L, Chitale DA, Barod R, Rogers CG, Kalyana-Sundaram S, Palanisamy N, Gupta NS, Williamson SR.Mod Pathol. 2017 Nov;30(11):1603-1612. doi: 10.1038/modpathol.2017.72. Epub 2017 Jul 21.PMID: 28731045 |
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Poor Prognosis Indicated by Venous Circulating Tumor Cell Clusters in Early-Stage Lung Cancers.Murlidhar V, Reddy RM, Fouladdel S, Zhao L, Ishikawa MK, Grabauskiene S, Zhang Z, Lin J, Chang AC, Carrott P, Lynch WR, Orringer MB, Kumar-Sinha C, Palanisamy N, Beer DG, Wicha MS, Ramnath N, Azizi E, Nagrath S.Cancer Res. 2017 Sep 15;77(18):5194-5206. doi: 10.1158/0008-5472.CAN-16-2072. Epub 2017 Jul 17.PMID: 28716896 Free PMC article. |
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Age and Gender Associations of Virus Positivity in Merkel Cell Carcinoma Characterized Using a Novel RNA In Situ Hybridization Assay.Wang L, Harms PW, Palanisamy N, Carskadon S, Cao X, Siddiqui J, Patel RM, Zelenka-Wang S, Durham AB, Fullen DR, Harms KL, Su F, Shukla S, Mehra R, Chinnaiyan AM.Clin Cancer Res. 2017 Sep 15;23(18):5622-5630. doi: 10.1158/1078-0432.CCR-17-0299. Epub 2017 Jun 12.PMID: 28606924 Free PMC article. |
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Renal Cell Carcinoma With Chromosome 6p Amplification Including the TFEB Gene: A Novel Mechanism of Tumor Pathogenesis?Williamson SR, Grignon DJ, Cheng L, Favazza L, Gondim DD, Carskadon S, Gupta NS, Chitale DA, Kalyana-Sundaram S, Palanisamy N.Am J Surg Pathol. 2017 Mar;41(3):287-298. doi: 10.1097/PAS.0000000000000776.PMID: 28009604 |
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Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer.Mani RS, Amin MA, Li X, Kalyana-Sundaram S, Veeneman BA, Wang L, Ghosh A, Aslam A, Ramanand SG, Rabquer BJ, Kimura W, Tran M, Cao X, Roychowdhury S, Dhanasekaran SM, Palanisamy N, Sadek HA, Kapur P, Koch AE, Chinnaiyan AM.Cell Rep. 2016 Dec 6;17(10):2620-2631. doi: 10.1016/j.celrep.2016.11.019.PMID: 27926866 Free PMC article. |
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Sclerosing TFEB-rearrangement renal cell carcinoma: a recurring histologic pattern.Williamson SR, Eble JN, Palanisamy N.Hum Pathol. 2017 Apr;62:175-179. doi: 10.1016/j.humpath.2016.10.024. Epub 2016 Nov 15.PMID: 27864122 |
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HER2 and EGFR Overexpression Support Metastatic Progression of Prostate Cancer to Bone.Day KC, Lorenzatti Hiles G, Kozminsky M, Dawsey SJ, Paul A, Broses LJ, Shah R, Kunja LP, Hall C, Palanisamy N, Daignault-Newton S, El-Sawy L, Wilson SJ, Chou A, Ignatoski KW, Keller E, Thomas D, Nagrath S, Morgan T, Day ML.Cancer Res. 2017 Jan 1;77(1):74-85. doi: 10.1158/0008-5472.CAN-16-1656. Epub 2016 Oct 28.PMID: 27793843 Free PMC article. |
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The utility of ETV1, ETV4 and ETV5 RNA in-situ hybridization in the diagnosis of CIC-DUX sarcomas.Smith SC, Palanisamy N, Martin E, Almenara J, McHugh JB, Choi EK, Lucas DR, Betz BL, Thomas D, Patel RM.Histopathology. 2017 Mar;70(4):657-663. doi: 10.1111/his.13112. Epub 2016 Dec 16.PMID: 27790742 |
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Correction: RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.Majumder M, House R, Palanisamy N, Qie S, Day TA, Neskey D, Diehl JA, Palanisamy V.PLoS Genet. 2016 Oct 26;12(10):e1006411. doi: 10.1371/journal.pgen.1006411. eCollection 2016 Oct.PMID: 27783624 Free PMC article. |
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Cultured circulating tumor cells and their derived xenografts for personalized oncology.Wang R, Chu GCY, Mrdenovic S, Annamalai AA, Hendifar AE, Nissen NN, Tomlinson JS, Lewis M, Palanisamy N, Tseng HR, Posadas EM, Freeman MR, Pandol SJ, Zhau HE, Chung LWK.Asian J Urol. 2016 Oct;3(4):240-253. doi: 10.1016/j.ajur.2016.08.005. Epub 2016 Aug 25.PMID: 29264192 Free PMC article. Review. |
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RNA-Binding Protein FXR1 Regulates p21 and TERC RNA to Bypass p53-Mediated Cellular Senescence in OSCC.Majumder M, House R, Palanisamy N, Qie S, Day TA, Neskey D, Diehl JA, Palanisamy V.PLoS Genet. 2016 Sep 8;12(9):e1006306. doi: 10.1371/journal.pgen.1006306. eCollection 2016 Sep.PMID: 27606879 Free PMC article. |
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Loss of p16 expression and copy number changes of CDKN2A in a spectrum of spitzoid melanocytic lesions.Harms PW, Hocker TL, Zhao L, Chan MP, Andea AA, Wang M, Harms KL, Wang ML, Carskadon S, Palanisamy N, Fullen DR.Hum Pathol. 2016 Dec;58:152-160. doi: 10.1016/j.humpath.2016.07.029. Epub 2016 Aug 26.PMID: 27569296 |
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Expression and Role of PAICS, a De Novo Purine Biosynthetic Gene in Prostate Cancer.Chakravarthi BV, Goswami MT, Pathi SS, Dodson M, Chandrashekar DS, Agarwal S, Nepal S, Hodigere Balasubramanya SA, Siddiqui J, Lonigro RJ, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S.Prostate. 2017 Jan;77(1):10-21. doi: 10.1002/pros.23243. Epub 2016 Aug 22.PMID: 27550065 |
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Expanded Circulating Tumor Cells from a Patient with ALK-Positive Lung Cancer Present with EML4-ALK Rearrangement Along with Resistance Mutation and Enable Drug Sensitivity Testing: A Case Study.Zhang Z, Shiratsuchi H, Palanisamy N, Nagrath S, Ramnath N.J Thorac Oncol. 2017 Feb;12(2):397-402. doi: 10.1016/j.jtho.2016.07.027. Epub 2016 Aug 6.PMID: 27507192 Free PMC article. |
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MicroRNA-101 regulated transcriptional modulator SUB1 plays a role in prostate cancer.Chakravarthi BV, Goswami MT, Pathi SS, Robinson AD, Cieślik M, Chandrashekar DS, Agarwal S, Siddiqui J, Daignault S, Carskadon SL, Jing X, Chinnaiyan AM, Kunju LP, Palanisamy N, Varambally S.Oncogene. 2016 Dec 8;35(49):6330-6340. doi: 10.1038/onc.2016.164. Epub 2016 Jun 6.PMID: 27270442 Free PMC article. |
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Tunable Thermal-Sensitive Polymer-Graphene Oxide Composite for Efficient Capture and Release of Viable Circulating Tumor Cells.Yoon HJ, Shanker A, Wang Y, Kozminsky M, Jin Q, Palanisamy N, Burness ML, Azizi E, Simeone DM, Wicha MS, Kim J, Nagrath S.Adv Mater. 2016 Jun;28(24):4891-7. doi: 10.1002/adma.201600658. Epub 2016 Apr 26.PMID: 27115557 Free PMC article. |
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Morpheaform Basal Cell Carcinomas With Areas of Predominantly Single-Cell Pattern of Infiltration: Diagnostic Utility of p63 and Cytokeratin.East E, Fullen DR, Arps D, Patel RM, Palanisamy N, Carskadon S, Harms PW.Am J Dermatopathol. 2016 Oct;38(10):744-50. doi: 10.1097/DAD.0000000000000541.PMID: 27043336 |
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Corrigendum: TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.Banerjee R, Russo N, Liu M, Basrur V, Bellile E, Palanisamy N, Scanlon CS, van Tubergen E, Inglehart RC, Metwally T, Mani RS, Yocum A, Nyati MK, Castilho RM, Varambally S, Chinnaiyan AM, D'Silva NJ.Nat Commun. 2016 Feb 24;7:10726. doi: 10.1038/ncomms10726.PMID: 26908012 Free PMC article. No abstract available. |
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47. |
Fibroblast growth factor family aberrations as a putative driver of head and neck squamous cell carcinoma in an epidemiologically low-risk patient as defined by targeted sequencing.Tillman BN, Yanik M, Birkeland AC, Liu CJ, Hovelson DH, Cani AK, Palanisamy N, Carskadon S, Carey TE, Bradford CR, Tomlins SA, McHugh JB, Spector ME, Brenner JCh.Head Neck. 2016 Apr;38 Suppl 1(Suppl 1):E1646-52. doi: 10.1002/hed.24292. Epub 2016 Feb 5.PMID: 26849095 Free PMC article. |
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48. |
Clonal evaluation of prostate cancer foci in biopsies with discontinuous tumor involvement by dual ERG/SPINK1 immunohistochemistry.Fontugne J, Davis K, Palanisamy N, Udager A, Mehra R, McDaniel AS, Siddiqui J, Rubin MA, Mosquera JM, Tomlins SA.Mod Pathol. 2016 Feb;29(2):157-65. doi: 10.1038/modpathol.2015.148. Epub 2016 Jan 8.PMID: 26743468 Free PMC article. |
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49. |
SPINK1 expression in relation to PTEN and ERG in matched primary and lymph node metastatic prostate cancer: Implications for biomarker development.Huang KC, Bégin LR, Palanisamy N, Donnelly B, Bismar TA.Urol Oncol. 2016 May;34(5):235.e1-10. doi: 10.1016/j.urolonc.2015.11.015. Epub 2015 Dec 22.PMID: 26725250 |
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A subset of solitary fibrous tumors express nuclear PAX8 and PAX2: a potential diagnostic pitfall.McDaniel AS, Palanisamy N, Smith SC, Robinson DR, Wu YM, Chinnaiyan AM, McHugh JB, Greenson JK, Kunju LP.Histol Histopathol. 2016 Feb;31(2):223-30. doi: 10.14670/HH-11-670. Epub 2015 Sep 26.PMID: 26404914 |
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51. |
Integrative Clinical Sequencing in the Management of Refractory or Relapsed Cancer in Youth.Mody RJ, Wu YM, Lonigro RJ, Cao X, Roychowdhury S, Vats P, Frank KM, Prensner JR, Asangani I, Palanisamy N, Dillman JR, Rabah RM, Kunju LP, Everett J, Raymond VM, Ning Y, Su F, Wang R, Stoffel EM, Innis JW, Roberts JS, Robertson PL, Yanik G, Chamdin A, Connelly JA, Choi S, Harris AC, Kitko C, Rao RJ, Levine JE, Castle VP, Hutchinson RJ, Talpaz M, Robinson DR, Chinnaiyan AM.JAMA. 2015 Sep 1;314(9):913-25. doi: 10.1001/jama.2015.10080.PMID: 26325560 Free PMC article. |
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The Distinctive Mutational Spectra of Polyomavirus-Negative Merkel Cell Carcinoma.Harms PW, Vats P, Verhaegen ME, Robinson DR, Wu YM, Dhanasekaran SM, Palanisamy N, Siddiqui J, Cao X, Su F, Wang R, Xiao H, Kunju LP, Mehra R, Tomlins SA, Fullen DR, Bichakjian CK, Johnson TM, Dlugosz AA, Chinnaiyan AM.Cancer Res. 2015 Sep 15;75(18):3720-3727. doi: 10.1158/0008-5472.CAN-15-0702. Epub 2015 Aug 3.PMID: 26238782 Free PMC article. |
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53. |
Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.Goswami MT, Chen G, Chakravarthi BV, Pathi SS, Anand SK, Carskadon SL, Giordano TJ, Chinnaiyan AM, Thomas DG, Palanisamy N, Beer DG, Varambally S.Oncotarget. 2015 Sep 15;6(27):23445-61. doi: 10.18632/oncotarget.4352.PMID: 26140362 Free PMC article. |
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Cytogenomic profiling of breast cancer brain metastases reveals potential for repurposing targeted therapeutics.Bollig-Fischer A, Michelhaugh SK, Wijesinghe P, Dyson G, Kruger A, Palanisamy N, Choi L, Alosh B, Ali-Fehmi R, Mittal S.Oncotarget. 2015 Jun 10;6(16):14614-24. doi: 10.18632/oncotarget.3786.PMID: 25970776 Free PMC article. |
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55. |
Extensive survey of STAT6 expression in a large series of mesenchymal tumors.Demicco EG, Harms PW, Patel RM, Smith SC, Ingram D, Torres K, Carskadon SL, Camelo-Piragua S, McHugh JB, Siddiqui J, Palanisamy N, Lucas DR, Lazar AJ, Wang WL.Am J Clin Pathol. 2015 May;143(5):672-82. doi: 10.1309/AJCPN25NJTOUNPNF.PMID: 25873501 Free PMC article. |
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56. |
Targeting the MLL complex in castration-resistant prostate cancer.Malik R, Khan AP, Asangani IA, Cieślik M, Prensner JR, Wang X, Iyer MK, Jiang X, Borkin D, Escara-Wilke J, Stender R, Wu YM, Niknafs YS, Jing X, Qiao Y, Palanisamy N, Kunju LP, Krishnamurthy PM, Yocum AK, Mellacheruvu D, Nesvizhskii AI, Cao X, Dhanasekaran SM, Feng FY, Grembecka J, Cierpicki T, Chinnaiyan AM.Nat Med. 2015 Apr;21(4):344-52. doi: 10.1038/nm.3830. Epub 2015 Mar 30.PMID: 25822367 Free PMC article. |
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57. |
Molecular profiling of ETS and non-ETS aberrations in prostate cancer patients from northern India.Ateeq B, Kunju LP, Carskadon SL, Pandey SK, Singh G, Pradeep I, Tandon V, Singhai A, Goel A, Amit S, Agarwal A, Dinda AK, Seth A, Tsodikov A, Chinnaiyan AM, Palanisamy N.Prostate. 2015 Jul 1;75(10):1051-62. doi: 10.1002/pros.22989. Epub 2015 Mar 23.PMID: 25809148 Free PMC article. |
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58. |
Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses.Harms PW, Fullen DR, Patel RM, Chang D, Shalin SC, Ma L, Wood B, Beer TW, Siddiqui J, Carskadon S, Wang M, Palanisamy N, Fisher GJ, Andea A.Hum Pathol. 2015 May;46(5):690-7. doi: 10.1016/j.humpath.2015.01.006. Epub 2015 Jan 14.PMID: 25704628 |
|
59. |
Interaction of the Androgen Receptor, ETV1, and PTEN Pathways in Mouse Prostate Varies with Pathological Stage and Predicts Cancer Progression.Higgins J, Brogley M, Palanisamy N, Mehra R, Ittmann MM, Li JZ, Tomlins SA, Robins DM.Horm Cancer. 2015 Jun;6(2-3):67-86. doi: 10.1007/s12672-014-0215-9. Epub 2015 Jan 29.PMID: 25631336 Free PMC article. |
|
60. |
Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes.Dhanasekaran SM, Balbin OA, Chen G, Nadal E, Kalyana-Sundaram S, Pan J, Veeneman B, Cao X, Malik R, Vats P, Wang R, Huang S, Zhong J, Jing X, Iyer M, Wu YM, Harms PW, Lin J, Reddy R, Brennan C, Palanisamy N, Chang AC, Truini A, Truini M, Robinson DR, Beer DG, Chinnaiyan AM.Nat Commun. 2014 Dec 22;5:5893. doi: 10.1038/ncomms6893.PMID: 25531467 Free PMC article. |
|
61. |
Small cell carcinoma in the parotid harboring Merkel cell polyomavirus.Fisher CA, Harms PW, McHugh JB, Edwards PC, Siddiqui J, Palanisamy N, Bichakjian CK, Benavides E, Danciu TE.Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Dec;118(6):703-12. doi: 10.1016/j.oooo.2014.09.012. Epub 2014 Sep 17.PMID: 25457888 |
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62. |
The oestrogen receptor alpha-regulated lncRNA NEAT1 is a critical modulator of prostate cancer.Chakravarty D, Sboner A, Nair SS, Giannopoulou E, Li R, Hennig S, Mosquera JM, Pauwels J, Park K, Kossai M, MacDonald TY, Fontugne J, Erho N, Vergara IA, Ghadessi M, Davicioni E, Jenkins RB, Palanisamy N, Chen Z, Nakagawa S, Hirose T, Bander NH, Beltran H, Fox AH, Elemento O, Rubin MA.Nat Commun. 2014 Nov 21;5:5383. doi: 10.1038/ncomms6383.PMID: 25415230 Free PMC article. |
|
63. |
Clear cell melanoma: a cutaneous clear cell malignancy.Pletneva MA, Andea A, Palanisamy N, Betz BL, Carskadon S, Wang M, Patel RM, Fullen DR, Harms PW.Arch Pathol Lab Med. 2014 Oct;138(10):1328-36. doi: 10.5858/arpa.2014-0307-CC.PMID: 25268196 Review. |
|
64. |
Determination of Optimum Formalin Fixation Duration for Prostate Needle Biopsies for Immunohistochemistry and Quantum Dot FISH Analysis.Sathyanarayana UG, Birch C, Nagle RB, Tomlins SA, Palanisamy N, Zhang W, Hubbard A, Brunhoeber P, Wang Y, Tang L.Appl Immunohistochem Mol Morphol. 2015 May-Jun;23(5):364-73. doi: 10.1097/PAI.0000000000000085.PMID: 25265431 |
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65. |
Expression of the p40 isoform of p63 has high specificity for cutaneous sarcomatoid squamous cell carcinoma.Ha Lan TT, Chen SJ, Arps DP, Fullen DR, Patel RM, Siddiqui J, Carskadon S, Palanisamy N, Harms PW.J Cutan Pathol. 2014 Nov;41(11):831-8. doi: 10.1111/cup.12387. Epub 2014 Nov 3.PMID: 25263756 |
|
66. |
Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer.Kunju LP, Carskadon S, Siddiqui J, Tomlins SA, Chinnaiyan AM, Palanisamy N.Appl Immunohistochem Mol Morphol. 2014 Sep;22(8):e32-40. doi: 10.1097/PAI.0000000000000095.PMID: 25203299 Free PMC article. |
|
67. |
Prostate cancer cell-stromal cell crosstalk via FGFR1 mediates antitumor activity of dovitinib in bone metastases.Wan X, Corn PG, Yang J, Palanisamy N, Starbuck MW, Efstathiou E, Li Ning Tapia EM, Zurita AJ, Aparicio A, Ravoori MK, Vazquez ES, Robinson DR, Wu YM, Cao X, Iyer MK, McKeehan W, Kundra V, Wang F, Troncoso P, Chinnaiyan AM, Logothetis CJ, Navone NM.Sci Transl Med. 2014 Sep 3;6(252):252ra122. doi: 10.1126/scitranslmed.3009332.PMID: 25186177 Free PMC article. |
|
68. |
Molecular profiling of ETS gene rearrangements in patients with prostate cancer registered in REDEEM clinical trial.Palanisamy N, Tsodikov A, Yan W, Suleman K, Rittmaster R, Lucia SM, Chinnaiyan AM, Fleshner N, Kunju LP.Urol Oncol. 2015 Mar;33(3):108.e5-13. doi: 10.1016/j.urolonc.2014.07.015. Epub 2014 Aug 28.PMID: 25175425 Clinical Trial. |
|
69. |
The miR-124-prolyl hydroxylase P4HA1-MMP1 axis plays a critical role in prostate cancer progression.Chakravarthi BV, Pathi SS, Goswami MT, Cieślik M, Zheng H, Nallasivam S, Arekapudi SR, Jing X, Siddiqui J, Athanikar J, Carskadon SL, Lonigro RJ, Kunju LP, Chinnaiyan AM, Palanisamy N, Varambally S.Oncotarget. 2014 Aug 30;5(16):6654-69. doi: 10.18632/oncotarget.2208.PMID: 25115393 Free PMC article. |
|
70. |
TRIP13 promotes error-prone nonhomologous end joining and induces chemoresistance in head and neck cancer.Banerjee R, Russo N, Liu M, Basrur V, Bellile E, Palanisamy N, Scanlon CS, van Tubergen E, Inglehart RC, Metwally T, Mani RS, Yocum A, Nyati MK, Castilho RM, Varambally S, Chinnaiyan AM, D'Silva NJ.Nat Commun. 2014 Jul 31;5:4527. doi: 10.1038/ncomms5527.PMID: 25078033 Free PMC article. |
|
71. |
Identification of a novel germline SPOP mutation in a family with hereditary prostate cancer.Zuhlke KA, Johnson AM, Tomlins SA, Palanisamy N, Carpten JD, Lange EM, Isaacs WB, Cooney KA.Prostate. 2014 Jun;74(9):983-90. doi: 10.1002/pros.22818. Epub 2014 May 6.PMID: 24796539 Free PMC article. |
|
72. |
HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey.Smith SC, Palanisamy N, Zuhlke KA, Johnson AM, Siddiqui J, Chinnaiyan AM, Kunju LP, Cooney KA, Tomlins SA.Am J Surg Pathol. 2014 May;38(5):615-26. doi: 10.1097/PAS.0000000000000090.PMID: 24722062 Free PMC article. |
|
73. |
At the intersection of primary pulmonary myxoid sarcoma and pulmonary angiomatoid fibrous histiocytoma: observations from three new cases.Smith SC, Palanisamy N, Betz BL, Tomlins SA, Mehra R, Schmidt LA, Lucas DR, Myers JL.Histopathology. 2014 Jul;65(1):144-6. doi: 10.1111/his.12354. Epub 2014 Mar 14.PMID: 24372335 No abstract available. |
|
74. |
Evaluation of tissue PCA3 expression in prostate cancer by RNA in situ hybridization--a correlative study with urine PCA3 and TMPRSS2-ERG.Warrick JI, Tomlins SA, Carskadon SL, Young AM, Siddiqui J, Wei JT, Chinnaiyan AM, Kunju LP, Palanisamy N.Mod Pathol. 2014 Apr;27(4):609-20. doi: 10.1038/modpathol.2013.169. Epub 2013 Sep 27.PMID: 24072184 Free PMC article. |
|
75. |
Comprehensive Analysis of ETS Family Members in Melanoma by Fluorescence In Situ Hybridization Reveals Recurrent ETV1 Amplification.Mehra R, Dhanasekaran SM, Palanisamy N, Vats P, Cao X, Kim JH, Kim DS, Johnson T, Fullen DR, Chinnaiyan AM.Transl Oncol. 2013 Aug 1;6(4):405-12. doi: 10.1593/tlo.13340. Print 2013 Aug.PMID: 23908683 Free PMC article. |
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76. |
Usefulness of a monoclonal ERG/FLI1 antibody for immunohistochemical discrimination of Ewing family tumors.Tomlins SA, Palanisamy N, Brenner JC, Stall JN, Siddiqui J, Thomas DG, Lucas DR, Chinnaiyan AM, Kunju LP.Am J Clin Pathol. 2013 Jun;139(6):771-9. doi: 10.1309/AJCPN4L1BMRQPEIT.PMID: 23690120 Free PMC article. |
|
77. |
HER2 drives luminal breast cancer stem cells in the absence of HER2 amplification: implications for efficacy of adjuvant trastuzumab.Ithimakin S, Day KC, Malik F, Zen Q, Dawsey SJ, Bersano-Begey TF, Quraishi AA, Ignatoski KW, Daignault S, Davis A, Hall CL, Palanisamy N, Heath AN, Tawakkol N, Luther TK, Clouthier SG, Chadwick WA, Day ML, Kleer CG, Thomas DG, Hayes DF, Korkaya H, Wicha MS.Cancer Res. 2013 Mar 1;73(5):1635-46. doi: 10.1158/0008-5472.CAN-12-3349. Epub 2013 Feb 26.PMID: 23442322 Free PMC article. |
|
78. |
Allelic imbalance in sporadic parathyroid carcinoma and evidence for its de novo origins.Costa-Guda J, Imanishi Y, Palanisamy N, Kawamata N, Phillip Koeffler H, Chaganti RS, Arnold A.Endocrine. 2013 Oct;44(2):489-95. doi: 10.1007/s12020-013-9903-4. Epub 2013 Feb 24.PMID: 23435613 Free PMC article. |
|
79. |
Recurrent reciprocal RNA chimera involving YPEL5 and PPP1CB in chronic lymphocytic leukemia.Velusamy T, Palanisamy N, Kalyana-Sundaram S, Sahasrabuddhe AA, Maher CA, Robinson DR, Bahler DW, Cornell TT, Wilson TE, Lim MS, Chinnaiyan AM, Elenitoba-Johnson KS.Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):3035-40. doi: 10.1073/pnas.1214326110. Epub 2013 Feb 4.PMID: 23382248 Free PMC article. |
|
80. |
Novel dual-color immunohistochemical methods for detecting ERG-PTEN and ERG-SPINK1 status in prostate carcinoma.Bhalla R, Kunju LP, Tomlins SA, Christopherson K, Cortez C, Carskadon S, Siddiqui J, Park K, Mosquera JM, Pestano GA, Rubin MA, Chinnaiyan AM, Palanisamy N.Mod Pathol. 2013 Jun;26(6):835-48. doi: 10.1038/modpathol.2012.234. Epub 2013 Jan 25.PMID: 23348902 Free PMC article. |
|
81. |
Characterization of the EZH2-MMSET histone methyltransferase regulatory axis in cancer.Asangani IA, Ateeq B, Cao Q, Dodson L, Pandhi M, Kunju LP, Mehra R, Lonigro RJ, Siddiqui J, Palanisamy N, Wu YM, Cao X, Kim JH, Zhao M, Qin ZS, Iyer MK, Maher CA, Kumar-Sinha C, Varambally S, Chinnaiyan AM.Mol Cell. 2013 Jan 10;49(1):80-93. doi: 10.1016/j.molcel.2012.10.008. Epub 2012 Nov 15.PMID: 23159737 Free PMC article. |
|
82. |
Role of transcriptional corepressor CtBP1 in prostate cancer progression.Wang R, Asangani IA, Chakravarthi BV, Ateeq B, Lonigro RJ, Cao Q, Mani RS, Camacho DF, McGregor N, Schumann TE, Jing X, Menawat R, Tomlins SA, Zheng H, Otte AP, Mehra R, Siddiqui J, Dhanasekaran SM, Nyati MK, Pienta KJ, Palanisamy N, Kunju LP, Rubin MA, Chinnaiyan AM, Varambally S.Neoplasia. 2012 Oct;14(10):905-14. doi: 10.1593/neo.121192.PMID: 23097625 Free PMC article. |
|
83. |
Correlation of urine TMPRSS2:ERG and PCA3 to ERG+ and total prostate cancer burden.Young A, Palanisamy N, Siddiqui J, Wood DP, Wei JT, Chinnaiyan AM, Kunju LP, Tomlins SA.Am J Clin Pathol. 2012 Nov;138(5):685-96. doi: 10.1309/AJCPU7PPWUPYG8OH.PMID: 23086769 Free PMC article. |
|
84. |
Gene fusions associated with recurrent amplicons represent a class of passenger aberrations in breast cancer.Kalyana-Sundaram S, Shankar S, Deroo S, Iyer MK, Palanisamy N, Chinnaiyan AM, Kumar-Sinha C.Neoplasia. 2012 Aug;14(8):702-8. doi: 10.1593/neo.12914.PMID: 22952423 Free PMC article. |
|
85. |
Genetic and epigenetic loss of microRNA-31 leads to feed-forward expression of EZH2 in melanoma.Asangani IA, Harms PW, Dodson L, Pandhi M, Kunju LP, Maher CA, Fullen DR, Johnson TM, Giordano TJ, Palanisamy N, Chinnaiyan AM.Oncotarget. 2012 Sep;3(9):1011-25. doi: 10.18632/oncotarget.622.PMID: 22948084 Free PMC article. |
|
86. |
Antibody-based detection of ERG rearrangements in prostate core biopsies, including diagnostically challenging cases: ERG staining in prostate core biopsies.Tomlins SA, Palanisamy N, Siddiqui J, Chinnaiyan AM, Kunju LP.Arch Pathol Lab Med. 2012 Aug;136(8):935-46. doi: 10.5858/arpa.2011-0424-OA.PMID: 22849743 Free PMC article. |
|
87. |
Expressed pseudogenes in the transcriptional landscape of human cancers.Kalyana-Sundaram S, Kumar-Sinha C, Shankar S, Robinson DR, Wu YM, Cao X, Asangani IA, Kothari V, Prensner JR, Lonigro RJ, Iyer MK, Barrette T, Shanmugam A, Dhanasekaran SM, Palanisamy N, Chinnaiyan AM.Cell. 2012 Jun 22;149(7):1622-34. doi: 10.1016/j.cell.2012.04.041.PMID: 22726445 Free PMC article. |
|
88. |
The mutational landscape of lethal castration-resistant prostate cancer.Grasso CS, Wu YM, Robinson DR, Cao X, Dhanasekaran SM, Khan AP, Quist MJ, Jing X, Lonigro RJ, Brenner JC, Asangani IA, Ateeq B, Chun SY, Siddiqui J, Sam L, Anstett M, Mehra R, Prensner JR, Palanisamy N, Ryslik GA, Vandin F, Raphael BJ, Kunju LP, Rhodes DR, Pienta KJ, Chinnaiyan AM, Tomlins SA.Nature. 2012 Jul 12;487(7406):239-43. doi: 10.1038/nature11125.PMID: 22722839 Free PMC article. |
|
89. |
Characterization of KRAS rearrangements in metastatic prostate cancer.Wang XS, Shankar S, Dhanasekaran SM, Ateeq B, Sasaki AT, Jing X, Robinson D, Cao Q, Prensner JR, Yocum AK, Wang R, Fries DF, Han B, Asangani IA, Cao X, Li Y, Omenn GS, Pflueger D, Gopalan A, Reuter VE, Kahoud ER, Cantley LC, Rubin MA, Palanisamy N, Varambally S, Chinnaiyan AM.Cancer Discov. 2011 Jun;1(1):35-43. doi: 10.1158/2159-8274.CD-10-0022. Epub 2011 Jun 1.PMID: 22140652 Free PMC article. |
|
90. |
Functionally recurrent rearrangements of the MAST kinase and Notch gene families in breast cancer.Robinson DR, Kalyana-Sundaram S, Wu YM, Shankar S, Cao X, Ateeq B, Asangani IA, Iyer M, Maher CA, Grasso CS, Lonigro RJ, Quist M, Siddiqui J, Mehra R, Jing X, Giordano TJ, Sabel MS, Kleer CG, Palanisamy N, Natrajan R, Lambros MB, Reis-Filho JS, Kumar-Sinha C, Chinnaiyan AM.Nat Med. 2011 Nov 20;17(12):1646-51. doi: 10.1038/nm.2580.PMID: 22101766 Free PMC article. |
|
91. |
Coordinated regulation of polycomb group complexes through microRNAs in cancer.Cao Q, Mani RS, Ateeq B, Dhanasekaran SM, Asangani IA, Prensner JR, Kim JH, Brenner JC, Jing X, Cao X, Wang R, Li Y, Dahiya A, Wang L, Pandhi M, Lonigro RJ, Wu YM, Tomlins SA, Palanisamy N, Qin Z, Yu J, Maher CA, Varambally S, Chinnaiyan AM.Cancer Cell. 2011 Aug 16;20(2):187-99. doi: 10.1016/j.ccr.2011.06.016.PMID: 21840484 Free PMC article. |
|
92. |
Decreased microRNA-214 levels in breast cancer cells coincides with increased cell proliferation, invasion and accumulation of the Polycomb Ezh2 methyltransferase.Derfoul A, Juan AH, Difilippantonio MJ, Palanisamy N, Ried T, Sartorelli V.Carcinogenesis. 2011 Nov;32(11):1607-14. doi: 10.1093/carcin/bgr184. Epub 2011 Aug 8.PMID: 21828058 Free PMC article. |
|
93. |
Urine TMPRSS2:ERG fusion transcript stratifies prostate cancer risk in men with elevated serum PSA.Tomlins SA, Aubin SM, Siddiqui J, Lonigro RJ, Sefton-Miller L, Miick S, Williamsen S, Hodge P, Meinke J, Blase A, Penabella Y, Day JR, Varambally R, Han B, Wood D, Wang L, Sanda MG, Rubin MA, Rhodes DR, Hollenbeck B, Sakamoto K, Silberstein JL, Fradet Y, Amberson JB, Meyers S, Palanisamy N, Rittenhouse H, Wei JT, Groskopf J, Chinnaiyan AM.Sci Transl Med. 2011 Aug 3;3(94):94ra72. doi: 10.1126/scitranslmed.3001970.PMID: 21813756 Free PMC article. |
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94. |
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression.Prensner JR, Iyer MK, Balbin OA, Dhanasekaran SM, Cao Q, Brenner JC, Laxman B, Asangani IA, Grasso CS, Kominsky HD, Cao X, Jing X, Wang X, Siddiqui J, Wei JT, Robinson D, Iyer HK, Palanisamy N, Maher CA, Chinnaiyan AM.Nat Biotechnol. 2011 Jul 31;29(8):742-9. doi: 10.1038/nbt.1914.PMID: 21804560 Free PMC article. |
|
95. |
Deep sequencing reveals distinct patterns of DNA methylation in prostate cancer.Kim JH, Dhanasekaran SM, Prensner JR, Cao X, Robinson D, Kalyana-Sundaram S, Huang C, Shankar S, Jing X, Iyer M, Hu M, Sam L, Grasso C, Maher CA, Palanisamy N, Mehra R, Kominsky HD, Siddiqui J, Yu J, Qin ZS, Chinnaiyan AM.Genome Res. 2011 Jul;21(7):1028-41. doi: 10.1101/gr.119347.110.PMID: 21724842 Free PMC article. |
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96. |
Mechanistic rationale for inhibition of poly(ADP-ribose) polymerase in ETS gene fusion-positive prostate cancer.Brenner JC, Ateeq B, Li Y, Yocum AK, Cao Q, Asangani IA, Patel S, Wang X, Liang H, Yu J, Palanisamy N, Siddiqui J, Yan W, Cao X, Mehra R, Sabolch A, Basrur V, Lonigro RJ, Yang J, Tomlins SA, Maher CA, Elenitoba-Johnson KS, Hussain M, Navone NM, Pienta KJ, Varambally S, Feng FY, Chinnaiyan AM.Cancer Cell. 2011 May 17;19(5):664-78. doi: 10.1016/j.ccr.2011.04.010.PMID: 21575865 Free PMC article. |
|
97. |
The tumor suppressor gene rap1GAP is silenced by miR-101-mediated EZH2 overexpression in invasive squamous cell carcinoma.Banerjee R, Mani RS, Russo N, Scanlon CS, Tsodikov A, Jing X, Cao Q, Palanisamy N, Metwally T, Inglehart RC, Tomlins S, Bradford C, Carey T, Wolf G, Kalyana-Sundaram S, Chinnaiyan AM, Varambally S, D'Silva NJ.Oncogene. 2011 Oct 20;30(42):4339-49. doi: 10.1038/onc.2011.141. Epub 2011 May 2.PMID: 21532618 Free PMC article. |
|
98. |
CD44-SLC1A2 gene fusions in gastric cancer.Tao J, Deng NT, Ramnarayanan K, Huang B, Oh HK, Leong SH, Lim SS, Tan IB, Ooi CH, Wu J, Lee M, Zhang S, Rha SY, Chung HC, Smoot DT, Ashktorab H, Kon OL, Cacheux V, Yap C, Palanisamy N, Tan P.Sci Transl Med. 2011 Apr 6;3(77):77ra30. doi: 10.1126/scitranslmed.3001423.PMID: 21471434 |
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99. |
Genomic loss of miR-486 regulates tumor progression and the OLFM4 antiapoptotic factor in gastric cancer.Oh HK, Tan AL, Das K, Ooi CH, Deng NT, Tan IB, Beillard E, Lee J, Ramnarayanan K, Rha SY, Palanisamy N, Voorhoeve PM, Tan P.Clin Cancer Res. 2011 May 1;17(9):2657-67. doi: 10.1158/1078-0432.CCR-10-3152. Epub 2011 Mar 17.PMID: 21415212 |
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100. |
Activation of NF-{kappa}B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4.Wang J, Cai Y, Shao LJ, Siddiqui J, Palanisamy N, Li R, Ren C, Ayala G, Ittmann M.Cancer Res. 2011 Feb 15;71(4):1325-33. doi: 10.1158/0008-5472.CAN-10-2210. Epub 2010 Dec 17.PMID: 21169414 Free PMC article. |
|
101. |
Chromosomal aberrations in solid tumors.Chinnaiyan AM, Palanisamy N.Prog Mol Biol Transl Sci. 2010;95:55-94. doi: 10.1016/B978-0-12-385071-3.00004-6.PMID: 21075329 Review. |
|
102. |
The neuronal repellent SLIT2 is a target for repression by EZH2 in prostate cancer.Yu J, Cao Q, Yu J, Wu L, Dallol A, Li J, Chen G, Grasso C, Cao X, Lonigro RJ, Varambally S, Mehra R, Palanisamy N, Wu JY, Latif F, Chinnaiyan AM.Oncogene. 2010 Sep 30;29(39):5370-80. doi: 10.1038/onc.2010.269. Epub 2010 Jul 12.PMID: 20622896 Free PMC article. |
|
103. |
Rearrangements of the RAF kinase pathway in prostate cancer, gastric cancer and melanoma.Palanisamy N, Ateeq B, Kalyana-Sundaram S, Pflueger D, Ramnarayanan K, Shankar S, Han B, Cao Q, Cao X, Suleman K, Kumar-Sinha C, Dhanasekaran SM, Chen YB, Esgueva R, Banerjee S, LaFargue CJ, Siddiqui J, Demichelis F, Moeller P, Bismar TA, Kuefer R, Fullen DR, Johnson TM, Greenson JK, Giordano TJ, Tan P, Tomlins SA, Varambally S, Rubin MA, Maher CA, Chinnaiyan AM.Nat Med. 2010 Jul;16(7):793-8. doi: 10.1038/nm.2166. Epub 2010 Jun 6.PMID: 20526349 Free PMC article. |
|
104. |
ETS gene aberrations in atypical cribriform lesions of the prostate: Implications for the distinction between intraductal carcinoma of the prostate and cribriform high-grade prostatic intraepithelial neoplasia.Han B, Suleman K, Wang L, Siddiqui J, Sercia L, Magi-Galluzzi C, Palanisamy N, Chinnaiyan AM, Zhou M, Shah RB.Am J Surg Pathol. 2010 Apr;34(4):478-85. doi: 10.1097/PAS.0b013e3181d6827b.PMID: 20220513 |
|
105. |
Induced chromosomal proximity and gene fusions in prostate cancer.Mani RS, Tomlins SA, Callahan K, Ghosh A, Nyati MK, Varambally S, Palanisamy N, Chinnaiyan AM.Science. 2009 Nov 27;326(5957):1230. doi: 10.1126/science.1178124. Epub 2009 Oct 29.PMID: 19933109 Free PMC article. |
|
106. |
An integrative approach to reveal driver gene fusions from paired-end sequencing data in cancer.Wang XS, Prensner JR, Chen G, Cao Q, Han B, Dhanasekaran SM, Ponnala R, Cao X, Varambally S, Thomas DG, Giordano TJ, Beer DG, Palanisamy N, Sartor MA, Omenn GS, Chinnaiyan AM.Nat Biotechnol. 2009 Nov;27(11):1005-11. doi: 10.1038/nbt.1584. Epub 2009 Nov 1.PMID: 19881495 Free PMC article. |
|
107. |
RCP is a human breast cancer-promoting gene with Ras-activating function.Zhang J, Liu X, Datta A, Govindarajan K, Tam WL, Han J, George J, Wong C, Ramnarayanan K, Phua TY, Leong WY, Chan YS, Palanisamy N, Liu ET, Karuturi KM, Lim B, Miller LD.J Clin Invest. 2009 Aug;119(8):2171-83. doi: 10.1172/JCI37622. Epub 2009 Jul 20.PMID: 19620787 Free PMC article. |
|
108. |
Chimeric transcript discovery by paired-end transcriptome sequencing.Maher CA, Palanisamy N, Brenner JC, Cao X, Kalyana-Sundaram S, Luo S, Khrebtukova I, Barrette TR, Grasso C, Yu J, Lonigro RJ, Schroth G, Kumar-Sinha C, Chinnaiyan AM.Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12353-8. doi: 10.1073/pnas.0904720106. Epub 2009 Jul 10.PMID: 19592507 Free PMC article. |
|
109. |
Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma.Han B, Mehra R, Suleman K, Tomlins SA, Wang L, Singhal N, Linetzky KA, Palanisamy N, Zhou M, Chinnaiyan AM, Shah RB.Mod Pathol. 2009 Sep;22(9):1176-85. doi: 10.1038/modpathol.2009.79. Epub 2009 May 22.PMID: 19465903 Free PMC article. |
|
110. |
Fluorescence in situ hybridization study shows association of PTEN deletion with ERG rearrangement during prostate cancer progression.Han B, Mehra R, Lonigro RJ, Wang L, Suleman K, Menon A, Palanisamy N, Tomlins SA, Chinnaiyan AM, Shah RB.Mod Pathol. 2009 Aug;22(8):1083-93. doi: 10.1038/modpathol.2009.69. Epub 2009 May 1.PMID: 19407851 Free PMC article. |
|
111. |
Inherent signals in sequencing-based Chromatin-ImmunoPrecipitation control libraries.Vega VB, Cheung E, Palanisamy N, Sung WK.PLoS One. 2009;4(4):e5241. doi: 10.1371/journal.pone.0005241. Epub 2009 Apr 15.PMID: 19367334 Free PMC article. |
|
112. |
Transcriptome sequencing to detect gene fusions in cancer.Maher CA, Kumar-Sinha C, Cao X, Kalyana-Sundaram S, Han B, Jing X, Sam L, Barrette T, Palanisamy N, Chinnaiyan AM.Nature. 2009 Mar 5;458(7234):97-101. doi: 10.1038/nature07638. Epub 2009 Jan 11.PMID: 19136943 Free PMC article. |
|
113. |
Chromosomal translocations in AML: detection and prognostic significance.Palanisamy N.Cancer Treat Res. 2010;145:41-58. doi: 10.1007/978-0-387-69259-3_3.PMID: 20306244 Review. No abstract available. |
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114. |
Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer.Varambally S, Cao Q, Mani RS, Shankar S, Wang X, Ateeq B, Laxman B, Cao X, Jing X, Ramnarayanan K, Brenner JC, Yu J, Kim JH, Han B, Tan P, Kumar-Sinha C, Lonigro RJ, Palanisamy N, Maher CA, Chinnaiyan AM.Science. 2008 Dec 12;322(5908):1695-9. doi: 10.1126/science.1165395. Epub 2008 Nov 13.PMID: 19008416 Free PMC article. |
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115. |
A fluorescence in situ hybridization screen for E26 transformation-specific aberrations: identification of DDX5-ETV4 fusion protein in prostate cancer.Han B, Mehra R, Dhanasekaran SM, Yu J, Menon A, Lonigro RJ, Wang X, Gong Y, Wang L, Shankar S, Laxman B, Shah RB, Varambally S, Palanisamy N, Tomlins SA, Kumar-Sinha C, Chinnaiyan AM.Cancer Res. 2008 Sep 15;68(18):7629-37. doi: 10.1158/0008-5472.CAN-08-2014.PMID: 18794152 Free PMC article. |
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116. |
Telomere-mediated genomic instability and the clinico-pathological parameters in breast cancer.Poonepalli A, Banerjee B, Ramnarayanan K, Palanisamy N, Putti TC, Hande MP.Genes Chromosomes Cancer. 2008 Dec;47(12):1098-109. doi: 10.1002/gcc.20608.PMID: 18720522 |
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117. |
Bevacizumab and rapamycin induce growth suppression in mouse models of hepatocellular carcinoma.Huynh H, Chow PK, Palanisamy N, Salto-Tellez M, Goh BC, Lee CK, Somani A, Lee HS, Kalpana R, Yu K, Tan PH, Wu J, Soong R, Lee MH, Hor H, Soo KC, Toh HC, Tan P.J Hepatol. 2008 Jul;49(1):52-60. doi: 10.1016/j.jhep.2008.02.022. Epub 2008 Apr 28.PMID: 18490075 |
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118. |
Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs).Ruan Y, Ooi HS, Choo SW, Chiu KP, Zhao XD, Srinivasan KG, Yao F, Choo CY, Liu J, Ariyaratne P, Bin WG, Kuznetsov VA, Shahab A, Sung WK, Bourque G, Palanisamy N, Wei CL.Genome Res. 2007 Jun;17(6):828-38. doi: 10.1101/gr.6018607.PMID: 17568001 Free PMC article. |
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119. |
Whole-genome cartography of estrogen receptor alpha binding sites.Lin CY, Vega VB, Thomsen JS, Zhang T, Kong SL, Xie M, Chiu KP, Lipovich L, Barnett DH, Stossi F, Yeo A, George J, Kuznetsov VA, Lee YK, Charn TH, Palanisamy N, Miller LD, Cheung E, Katzenellenbogen BS, Ruan Y, Bourque G, Wei CL, Liu ET.PLoS Genet. 2007 Jun;3(6):e87. doi: 10.1371/journal.pgen.0030087. Epub 2007 Apr 17.PMID: 17542648 Free PMC article. |
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120. |
Baculoviral vector-mediated transient and stable transgene expression in human embryonic stem cells.Zeng J, Du J, Zhao Y, Palanisamy N, Wang S.Stem Cells. 2007 Apr;25(4):1055-61. doi: 10.1634/stemcells.2006-0616.PMID: 17420229 |
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121. |
Targets of genome copy number reduction in primary breast cancers identified by integrative genomics.Chen W, Salto-Tellez M, Palanisamy N, Ganesan K, Hou Q, Tan LK, Sii LH, Ito K, Tan B, Wu J, Tay A, Tan KC, Ang E, Tan BK, Tan PH, Ito Y, Tan P.Genes Chromosomes Cancer. 2007 Mar;46(3):288-301. doi: 10.1002/gcc.20411.PMID: 17171680 |
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122. |
Derivation of clinically compliant MSCs from CD105+, CD24- differentiated human ESCs.Lian Q, Lye E, Suan Yeo K, Khia Way Tan E, Salto-Tellez M, Liu TM, Palanisamy N, El Oakley RM, Lee EH, Lim B, Lim SK.Stem Cells. 2007 Feb;25(2):425-36. doi: 10.1634/stemcells.2006-0420. Epub 2006 Oct 19.PMID: 17053208 |
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123. |
Genomic amplification of the human telomerase gene (TERC) in pap smears predicts the development of cervical cancer.Heselmeyer-Haddad K, Sommerfeld K, White NM, Chaudhri N, Morrison LE, Palanisamy N, Wang ZY, Auer G, Steinberg W, Ried T.Am J Pathol. 2005 Apr;166(4):1229-38. doi: 10.1016/S0002-9440(10)62341-3.PMID: 15793301 Free PMC article. |
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124. |
Deregulation of the carbohydrate (chondroitin 4) sulfotransferase 11 (CHST11) gene in a B-cell chronic lymphocytic leukemia with a t(12;14)(q23;q32).Schmidt HH, Dyomin VG, Palanisamy N, Itoyama T, Nanjangud G, Pirc-Danoewinata H, Haas OA, Chaganti RS.Oncogene. 2004 Sep 9;23(41):6991-6. doi: 10.1038/sj.onc.1207934.PMID: 15273723 |
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125. |
Relationship between REL amplification, REL function, and clinical and biologic features in diffuse large B-cell lymphomas.Houldsworth J, Olshen AB, Cattoretti G, Donnelly GB, Teruya-Feldstein J, Qin J, Palanisamy N, Shen Y, Dyomina K, Petlakh M, Pan Q, Zelenetz AD, Dalla-Favera R, Chaganti RS.Blood. 2004 Mar 1;103(5):1862-8. doi: 10.1182/blood-2003-04-1359. Epub 2003 Nov 13.PMID: 14615382 |
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126. |
Mutational analyses of RB and BRCA2 as candidate tumour suppressor genes in parathyroid carcinoma.Shattuck TM, Kim TS, Costa J, Yandell DW, Imanishi Y, Palanisamy N, Gaz RD, Shoback D, Clark OH, Monchik JM, Wierman ME, Hollenberg A, Tojo K, Chaganti RS, Arnold A.Clin Endocrinol (Oxf). 2003 Aug;59(2):180-9. doi: 10.1046/j.1365-2265.2003.01814.x.PMID: 12864795 |
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127. |
BCL8 is a novel, evolutionarily conserved human gene family encoding proteins with presumptive protein kinase A anchoring function.Dyomin VG, Chaganti SR, Dyomina K, Palanisamy N, Murty VV, Dalla-Favera R, Chaganti RS.Genomics. 2002 Aug;80(2):158-65. doi: 10.1006/geno.2002.6822.PMID: 12160729 |
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128. |
Alternative translocation breakpoint cluster region 5' to BCL-6 in B-cell non-Hodgkin's lymphoma.Butler MP, Iida S, Capello D, Rossi D, Rao PH, Nallasivam P, Louie DC, Chaganti S, Au T, Gascoyne RD, Gaidano G, Chaganti RS, Dalla-Favera R.Cancer Res. 2002 Jul 15;62(14):4089-94.PMID: 12124346 |
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129. |
Clonal chromosomal defects in the molecular pathogenesis of refractory hyperparathyroidism of uremia.Imanishi Y, Tahara H, Palanisamy N, Spitalny S, Salusky IB, Goodman W, Brandi ML, Drüeke TB, Sarfati E, Ureña P, Chaganti RS, Arnold A.J Am Soc Nephrol. 2002 Jun;13(6):1490-8. doi: 10.1097/01.asn.0000018148.50109.c0.PMID: 12039978 |
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130. |
Similar patterns of genomic alterations characterize primary mediastinal large-B-cell lymphoma and diffuse large-B-cell lymphoma.Palanisamy N, Abou-Elella AA, Chaganti SR, Houldsworth J, Offit K, Louie DC, Terayu-Feldstein J, Cigudosa JC, Rao PH, Sanger WG, Weisenburger DD, Chaganti RS.Genes Chromosomes Cancer. 2002 Feb;33(2):114-22. doi: 10.1002/gcc.10016.PMID: 11793437 |
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131. |
Deregulation of FCGR2B expression by 1q21 rearrangements in follicular lymphomas.Chen W, Palanisamy N, Schmidt H, Teruya-Feldstein J, Jhanwar SC, Zelenetz AD, Houldsworth J, Chaganti RS.Oncogene. 2001 Nov 15;20(52):7686-93. doi: 10.1038/sj.onc.1204989.PMID: 11753646 |
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132. |
IRTA1 and IRTA2, novel immunoglobulin superfamily receptors expressed in B cells and involved in chromosome 1q21 abnormalities in B cell malignancy.Hatzivassiliou G, Miller I, Takizawa J, Palanisamy N, Rao PH, Iida S, Tagawa S, Taniwaki M, Russo J, Neri A, Cattoretti G, Clynes R, Mendelsohn C, Chaganti RS, Dalla-Favera R.Immunity. 2001 Mar;14(3):277-89. doi: 10.1016/s1074-7613(01)00109-1.PMID: 11290337 |
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133. |
MUC1 is activated in a B-cell lymphoma by the t(1;14)(q21;q32) translocation and is rearranged and amplified in B-cell lymphoma subsets.Dyomin VG, Palanisamy N, Lloyd KO, Dyomina K, Jhanwar SC, Houldsworth J, Chaganti RS.Blood. 2000 Apr 15;95(8):2666-71.PMID: 10753849 |
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134. |
Vitamin D receptor as a candidate tumor-suppressor gene in severe hyperparathyroidism of uremia.Brown SB, Brierley TT, Palanisamy N, Salusky IB, Goodman W, Brandi ML, Drüeke TB, Sarfati E, Ureña P, Chaganti RS, Pike JW, Arnold A.J Clin Endocrinol Metab. 2000 Feb;85(2):868-72. doi: 10.1210/jcem.85.2.6426.PMID: 10690903 |
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135. |
A common molecular basis for rearrangement disorders on chromosome 22q11.Edelmann L, Pandita RK, Spiteri E, Funke B, Goldberg R, Palanisamy N, Chaganti RS, Magenis E, Shprintzen RJ, Morrow BE.Hum Mol Genet. 1999 Jul;8(7):1157-67. doi: 10.1093/hmg/8.7.1157.PMID: 10369860 |
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136. |
Chromosomal amplification is associated with cisplatin resistance of human male germ cell tumors.Rao PH, Houldsworth J, Palanisamy N, Murty VV, Reuter VE, Motzer RJ, Bosl GJ, Chaganti RS.Cancer Res. 1998 Oct 1;58(19):4260-3.PMID: 9766648 |
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137. |
Novel chromosomal abnormalities identified by comparative genomic hybridization in parathyroid adenomas.Palanisamy N, Imanishi Y, Rao PH, Tahara H, Chaganti RS, Arnold A.J Clin Endocrinol Metab. 1998 May;83(5):1766-70. doi: 10.1210/jcem.83.5.4806.PMID: 9589690 |
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138. |
Genomic organization and allelic polymorphism of the human killer cell inhibitory receptor gene KIR103.Selvakumar A, Steffens U, Palanisamy N, Chaganti RS, Dupont B.Tissue Antigens. 1997 Jun;49(6):564-73. doi: 10.1111/j.1399-0039.1997.tb02803.x.PMID: 9234477 |
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139. |
The t(9;14)(p13;q32) chromosomal translocation associated with lymphoplasmacytoid lymphoma involves the PAX-5 gene.Iida S, Rao PH, Nallasivam P, Hibshoosh H, Butler M, Louie DC, Dyomin V, Ohno H, Chaganti RS, Dalla-Favera R Blood. 1996 Dec 1;88(11):4110-7.PMID: 8943844 |
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140. |
Human smooth muscle myosin heavy chain isoforms as molecular markers for vascular development and atherosclerosis.Aikawa M, Sivam PN, Kuro-o M, Kimura K, Nakahara K, Takewaki S, Ueda M, Yamaguchi H, Yazaki Y, Periasamy M, et al.Circ Res. 1993 Dec;73(6):1000-12. doi: 10.1161/01.res.73.6.1000.PMID: 7916668 |
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141. |
Cornelia de Lange syndrome with ring chromosome 3.Lakshminarayana P, Nallasivam P.J Med Genet. 1990 Jun;27(6):405-6. doi: 10.1136/jmg.27.6.405.PMID: 2359108 Free PMC article. No abstract available. |
